Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077421 | 0.93 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL8067467 | 0.91 | MAPT (0.39) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL8729302 | 0.90 | MAPT (0.44) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL8724364 | 0.90 | MAPT (0.47) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL8728075 | 0.89 | MAPT (0.45) | MAPTSMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL8075449 | 0.89 | MAPT (0.43) | MAPTTHRBHPGDALDH1A1L3MBTL1 | |
| SCHEMBL8081986 | 0.87 | ALDH1A1 (0.46) | MAPTSMN1; SMN2THRBHPGDALDH1A1 | |
| SCHEMBL8077327 | 0.87 | ALDH1A1 (0.46) | MAPTSMN1; SMN2THRBHPGDALDH1A1 | |
| SCHEMBL8080490 | 0.87 | ALDH1A1 (0.46) | MAPTSMN1; SMN2THRBHPGDALDH1A1 | |
| SCHEMBL8077341 | 0.87 | ALDH1A1 (0.46) | MAPTSMN1; SMN2THRBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755918-B1 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | ROLIC AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| US-5800733-A | Photo cross-linkable liquid crystal derivatives | ROLIC AG (CH) | 1998-09-01 | — | — | US | disclosed |
| EP-0755918-A2 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | Rolic AG (CH) | 1997-01-29 | — | — | EP | disclosed |