Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729402 | 0.93 | THRB (0.46) | THRBTHRARARBSMN1; SMN2MAPT | |
| SCHEMBL8729325 | 0.90 | THRB (0.44) | THRBTHRARARBSMN1; SMN2MAPT | |
| SCHEMBL816233 | 0.89 | THRB (0.52) | THRBRARBTSHRHTTCYP3A4 | |
| SCHEMBL8725719 | 0.87 | PPARD (0.48) | THRBTHRAPPARDRARBMAPT | |
| SCHEMBL15398104 | 0.87 | THRB (0.44) | THRBTHRARARBTSHRHTT | |
| SCHEMBL12975852 | 0.86 | NPC1 (0.45) | THRBTHRASMN1; SMN2MAPTNPC1 | |
| SCHEMBL30636399 | 0.85 | THRB (0.56) | THRBSMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL13138635 | 0.85 | NPC1 (0.44) | THRBPPARDSMN1; SMN2MAPTNPC1 | |
| SCHEMBL12975801 | 0.84 | THRB (0.46) | THRBTHRASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8077092 | 0.84 | MAPT (0.47) | THRBRARBSMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800733-A | Photo cross-linkable liquid crystal derivatives | ROLIC AG (CH) | 1998-09-01 | — | — | US | disclosed |