Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729321 | 0.93 | THRB (0.51) | THRBTHRARARBHPGDMAPT | |
| SCHEMBL816233 | 0.91 | THRB (0.52) | THRBRARBL3MBTL1HTTTSHR | |
| SCHEMBL15398104 | 0.90 | THRB (0.44) | THRBTHRARARBL3MBTL1HTT | |
| SCHEMBL8729405 | 0.89 | THRB (0.44) | THRBRARBHPGDMAPTHTT | |
| SCHEMBL30636399 | 0.88 | THRB (0.56) | THRBHPGDMAPTL3MBTL1HTT | |
| SCHEMBL8728233 | 0.86 | THRB (0.47) | THRBTHRARARBHPGDMAPT | |
| SCHEMBL8067413 | 0.86 | THRB (0.53) | THRBHPGDMAPTL3MBTL1HTT | |
| SCHEMBL8080543 | 0.85 | MAPT (0.44) | THRBRARBHPGDMAPTL3MBTL1 | |
| SCHEMBL31520193 | 0.85 | NPC1 (0.45) | THRBHPGDMAPTHTTLMNA | |
| SCHEMBL13921926 | 0.85 | NPC1 (0.45) | THRBHPGDMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800733-A | Photo cross-linkable liquid crystal derivatives | ROLIC AG (CH) | 1998-09-01 | — | — | US | disclosed |