Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | SCD | O00767 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18550707 | 0.87 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3314994 | 0.86 | KDM4E (0.80) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9133379 | 0.79 | GAA (0.74) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8732999 | 0.78 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3053529 | 0.78 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30598987 | 0.76 | KDM4E (0.76) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26115749 | 0.76 | KDM4E (0.76) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28591554 | 0.73 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL17916702 | 0.73 | SCD (1.00) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL16587876 | 0.73 | EPHX1 (0.69) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6305964-A | — | — | None | — | — | JP | disclosed |
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| JP-H06305964-A | INHIBITOR OF MAILLARD REACTION | OTSUKA PHARMACEUT CO LTD | 1994-11-01 | — | — | JP | disclosed |