SCHEMBL3314994

SCHEMBL3314994

O=C(NNc1nc2ccccc2s1)c1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.80
▸ LMNA P02545 2/20 0.80
▸ NPC1 O15118 6/20 0.73
▸ RAB9A P51151 6/20 0.73
▸ SMN1; SMN2 Q16637 5/20 0.73
▸ MEN1 O00255 3/20 0.73
▸ KMT2A Q03164 3/20 0.73
▸ SCD O00767 2/20 0.70
▸ GAA P10253 8/20 0.68
▸ CYP1A2 P05177 3/20 0.68
▸ ALDH1A1 P00352 5/20 0.67
▸ HTT P42858 3/20 0.67
▸ CYP2C19 P33261 2/20 0.67
▸ CYP2C9 P11712 1/20 0.67
▸ GFER P55789 1/20 0.67
▸ MAPT P10636 4/20 0.66
▸ HPGD P15428 2/20 0.66
▸ PKM P14618 1/20 0.65
▸ MAPK1 P28482 1/20 0.63
▸ CSNK1D P48730 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30598987 0.89 KDM4E (0.76) KDM4ELMNANPC1RAB9ASMN1; SMN2
SCHEMBL26115749 0.89 KDM4E (0.76) KDM4ELMNANPC1RAB9ASMN1; SMN2
SCHEMBL8729336 0.86 NPC1 (0.63) KDM4ELMNANPC1RAB9ASMN1; SMN2
SCHEMBL9133379 0.86 GAA (0.74) KDM4ELMNANPC1RAB9ASMN1; SMN2
SCHEMBL3053529 0.84 NPC1 (1.00) KDM4ENPC1RAB9ASMN1; SMN2MEN1
SCHEMBL17916702 0.82 SCD (1.00) KDM4ENPC1RAB9ASMN1; SMN2MEN1
SCHEMBL2625445 0.82 BCL2L1 (0.60) KDM4ELMNANPC1RAB9ASMN1; SMN2
SCHEMBL28473275 0.79 KDM4E (0.66) KDM4ELMNANPC1RAB9ASMN1; SMN2
SCHEMBL27692836 0.78 GAA (0.68) KDM4ELMNANPC1RAB9ASMN1; SMN2
SCHEMBL16562172 0.78 NPC1 (0.86) KDM4ENPC1RAB9ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1656551-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR Honeywell International Inc. (US) 2006-05-17 — — EP claimed
WO-2005019816-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR HONEYWELL INTERNATIONAL, INC. (US) 2005-03-03 — — WO claimed
US-20050042758-A1 Leak detection method using microencapsulated dye precursor HONEYWELL CORPORATION 2005-02-24 — — US claimed
US-4650740-A DIAZONIUM SALT AND COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1987-03-17 — — US claimed
EP-1260498-B1 NOVEL COLOR FORMER AND RECORDING MATERIAL CHEMIPRO KASEI KAISHA LTD (JP) 2014-07-09 — — EP disclosed
CN-101003499-B Novel color former and recording material ASAHI CHEMICAL IND 2011-01-19 — — CN disclosed
US-7807738-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2010-10-05 — — US disclosed
US-20100105941-A1 NOVEL COMPOUND FOR COLOR-PRODUCING COMPOSITION, AND RECORDING MATERIAL KABASHIMA KAZUO 2010-04-29 — — US disclosed
US-7635662-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2009-12-22 — — US disclosed
CN-100532120-C Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO LTD (JP) 2009-08-26 — — CN disclosed
US-7270928-B2 Isocyanate composition, microcapsule and production method thereof, and recording material FUJIFILM CORPORATION (JP) 2007-09-18 — — US disclosed
CN-101003499-A Novel color former and recording material ASAHI CHEMICAL IND (JP) 2007-07-25 — — CN disclosed
EP-0262953-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-04-06 — — EP disclosed
US-4665411-A MICROENCAPSULATED DIAZO COMPOUND AND COUPLER, DIELECTRIC SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1987-05-12 — — US disclosed
EP-0109838-B1 LIGHT AND HEAT-SENSITIVE RECORDING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1987-04-08 — — EP disclosed
US-4650740-A DIAZONIUM SALT AND COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1987-03-17 — — US disclosed
US-4644376-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-02-17 — — US disclosed
US-4529681-A Microcapsules containing vinyl compound, photoinitiator and color forming compound FUJI PHOTO FILM CO., LTD. (JP) 1985-07-16 — — US disclosed
EP-0123224-A2 Heat sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1984-10-31 — — EP disclosed
EP-0109838-A2 Light and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1984-05-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105941-A1 NOVEL COMPOUND FOR COLOR-PRODUCING COMPOSITION, AND RECORDING MATERIAL UMPS, UROD, UGP2 KDM4E 1348/4885LMNA 1474/4885NPC1 4357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback