Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11796169 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL28117082 | 0.75 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL9778185 | 0.72 | SMN1; SMN2 (0.33) | SMN1; SMN2LMNATSHRALDH1A1HSD17B10 | |
| 1,4-Butanediol SCHEMBL2540991 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNATSHRALDH1A1HSD17B10 | |
| 1,4-Butanediol SCHEMBL29165974 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL811921 | 0.72 | TSHR (0.35) | LMNATSHRCHRM1AKR1A1CHRM3 | |
| SCHEMBL8403161 | 0.71 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNATSHRALDH1A1HSD17B10 | |
| 1,6-Hexanediol SCHEMBL6363325 | 0.70 | LMNA (0.55) | SMN1; SMN2LMNATSHRALDH1A1HSD17B10 | |
| 1,4-Butanediol SCHEMBL28070212 | 0.70 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL8897031 | 0.70 | TSHR (0.35) | SMN1; SMN2LMNATSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619802-B1 | A MIXTURE OF HIGHER PRIMARY ALIPHATIC ALCOHOLS AND ITS PHARMACEUTICAL USES | DALMER LAB SA (CU) | 1998-11-04 | — | — | EP | disclosed |