SCHEMBL8403161

SCHEMBL8403161

CCCC(O)C(CC)(CO)C(O)CCCCO

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 5/20 0.34
ALDH1A1 P00352 3/20 0.34
TSHR P16473 2/20 0.34
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP2D6 P10635 2/20 0.32
SPHK1 Q9NYA1 1/20 0.32
GMNN O75496 1/20 0.32
POLB P06746 1/20 0.32
THPO P40225 1/20 0.32
MTOR P42345 1/20 0.32
BLM P54132 1/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
CETP P11597 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6812752 0.84 LMNA (0.50) LMNAALDH1A1MEN1KMT2ACYP2D6
SCHEMBL18759644 0.76 TSHR (0.35) LMNATSHRCYP3A4
SCHEMBL17464892 0.73 TSHR (0.44) LMNAALDH1A1TSHR
SCHEMBL11796169 0.72 SMN1; SMN2 (0.39) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL14949770 0.71 SMN1; SMN2 (0.36) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL8729348 0.71 SMN1; SMN2 (0.42) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL18759589 0.70 TSHR (0.42) LMNAALDH1A1TSHR
SCHEMBL21552250 0.69 LMNA (0.48) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL13464099 0.69 LMNA (0.48) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL5705598 0.68 THRB (0.42) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5932200-A ANTIPERSPIRANTS, DEODORANTS, COSMETICS TYNDALE PLAINS-HUNTER, LTD. (US) 1999-08-03 US disclosed
US-5728762-A POLYETHERURETHANES FOR ABSORBERS FORMED BY HEATING AND COOLING TYNDALE PLAINS-HUNTER, LTD. (US) 1998-03-17 US disclosed
EP-0792304-A4 POLYETHER POLYURETHANE POLYMERS, GELS, SOLUTIONS AND USES THEREOF TYNDALE PLAINS HUNTER LTD TYND (US) 1998-03-11 EP disclosed
EP-0792304-A1 POLYETHER POLYURETHANE POLYMERS, GELS, SOLUTIONS AND USES THEREOF TYNDALE PLAINS-HUNTER, LTD. (US) 1997-09-03 EP disclosed
US-5563233-A HYDROPHILIC POLYMER TYNDALE PLAINS-HUNTER, LTD. (US) 1996-10-08 US disclosed
WO-1996015171-A1 POLYETHER POLYURETHANE POLYMERS, GELS, SOLUTIONS AND USES THEREOF TYNDALE PLAINS-HUNTER, LTD. (US) 1996-05-23 WO disclosed