Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678571 | 0.90 | SRD5A2 (0.46) | GAATSHRSRD5A2RAB9ACYP1A2 | |
| SCHEMBL1764282 | 0.83 | ALDH1A1 (0.47) | LMNAGAAPTGS1SRD5A2SMN1; SMN2 | |
| SCHEMBL7674517 | 0.83 | LTA4H (0.43) | SRD5A2RAB9APTPN1HSD17B10HPGD | |
| SCHEMBL7678834 | 0.83 | HPGD (0.48) | TSHRHTTSRD5A2SMN1; SMN2RAB9A | |
| SCHEMBL7676938 | 0.80 | MAPT (0.52) | LMNAGAATSHRSRD5A2RAB9A | |
| SCHEMBL8732360 | 0.78 | CDC25B (0.55) | LMNASRD5A2SMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL10911413 | 0.76 | TSHR (0.47) | GAATSHRSRD5A2SMN1; SMN2RAB9A | |
| SCHEMBL11811712 | 0.75 | HDAC8 (0.47) | MEN1KMT2AHSD17B10 | |
| SCHEMBL11295460 | 0.74 | FFAR1 (0.43) | GAATSHRSRD5A2SMN1; SMN2FFAR1 | |
| SCHEMBL11813950 | 0.74 | TSHR (0.45) | LMNAABCC4TSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783488-A4 | FIVE MEMBERED HETEROCYCLIC COMPOUNDS | ONO PHARMACEUTICAL CO (JP) | 1998-01-07 | — | — | EP | claimed |
| EP-0783488-A1 | FIVE MEMBERED HETEROCYCLIC COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-07-16 | — | — | EP | claimed |
| WO-1996010013-A1 | FIVE MEMBERED HETEROCYCLIC COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-04-04 | — | — | WO | claimed |