SCHEMBL8729658

SCHEMBL8729658

O=S(=O)(OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.37
CA1 P00915 7/20 0.37
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2959329 1.00 CA2 (0.37) CA2CA1MMP1MMP2MMP9
SCHEMBL7672107 0.98 CA2 (0.37) CA2CA1
SCHEMBL15665290 0.84 CA2 (0.40) CA2CA1
SCHEMBL5671896 0.81 CA2 (0.34) CA2CA1MMP1MMP2MMP9
SCHEMBL28603425 0.81 CA2 (0.42) CA2CA1
SCHEMBL4473443 0.81 MMP9 (0.41) CA2CA1MMP1MMP2MMP9
SCHEMBL9148542 0.80 CA1 (0.35) CA2CA1
SCHEMBL9141595 0.80 CA2 (0.34) CA2CA1MMP1MMP2MMP9
SCHEMBL3032133 0.80 CA2 (0.34) CA2CA1MMP1MMP2MMP9
SCHEMBL12476991 0.80 CA2 (0.34) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170038680-A1 FLUORINATED PHOTORESIST WITH INTEGRATED SENSITIZER ORTHOGONAL, INC. 2017-02-09 US disclosed
US-9500948-B2 Fluorinated photoresist with integrated sensitizer ORTHOGONAL, INC. (US) 2016-11-22 US disclosed
US-9298088-B2 Fluorinated photopolymer with fluorinated sensitizer ORTHOGONAL, INC. (US) 2016-03-29 US disclosed
US-20150030982-A1 FLUORINATED PHOTOPOLYMER WITH FLUORINATED SENSITIZER ORTHOGONAL, INC. 2015-01-29 US disclosed
US-20140356788-A1 FLUORINATED PHOTORESIST WITH INTEGRATED SENSITIZER ORTHOGONAL, INC. 2014-12-04 US disclosed
US-5814378-A ACRYLATED ESTER OF A BIPHENYL COMPOUND SHARP KABUSHIKI KAISHA (JP) 1998-09-29 US disclosed