Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.60 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | PTGIR | P43119 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1832083 | 0.87 | ALOX15 (0.77) | KMT2AMEN1ALDH1A1MAPTPTPN7 | |
| SCHEMBL11649939 | 0.84 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1MAPTPTPN7 | |
| Hydrochloric Acid SCHEMBL5903375 | 0.84 | ALOX15 (0.63) | KMT2AMEN1ALDH1A1MAPTPTPN7 | |
| Hydrochloric Acid SCHEMBL11104858 | 0.84 | ALOX15 (0.63) | KMT2AMEN1ALDH1A1MAPTPTPN7 | |
| Chlorobenzene SCHEMBL7068183 | 0.82 | ALOX15 (0.80) | KMT2AMEN1ALDH1A1MAPTPTPN7 | |
| SCHEMBL40485 | 0.82 | ALOX15 (0.65) | KMT2AMEN1ALDH1A1MAPTPTPN7 | |
| SCHEMBL30969690 | 0.82 | ALOX15 (0.65) | KMT2AMEN1ALDH1A1MAPTPTPN7 | |
| SCHEMBL31134770 | 0.81 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1MAPTPTPN7 | |
| SCHEMBL29240036 | 0.81 | ALOX15 (0.63) | KMT2AMEN1ALDH1A1MAPTPTPN7 | |
| Ammonia Solution, Strong SCHEMBL28895431 | 0.81 | ALOX15 (0.63) | KMT2AMEN1ALDH1A1MAPTPTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |