SCHEMBL87299

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL86220	0.85	ALDH1A1 (0.47)	ALDH1A1MAPTTDP1L3MBTL1POLB
	SCHEMBL23699575	0.77	ALDH1A1 (0.54)	ALDH1A1MAPTTDP1L3MBTL1POLB
	SCHEMBL10057989	0.74	MAPT (0.63)	ALDH1A1MAPTTDP1L3MBTL1POLB
	SCHEMBL17433226	0.73	GPR3 (0.67)	ALDH1A1MAPTTDP1L3MBTL1POLB
	SCHEMBL18533299	0.73	GPR3 (0.41)	ALDH1A1MAPTTDP1L3MBTL1POLB
	SCHEMBL87204	0.72	AHR (0.45)	ALDH1A1MAPTRAB9AHPGDSMN1; SMN2
	SCHEMBL86077	0.72	ALDH1A1 (0.46)	ALDH1A1MAPTTDP1L3MBTL1POLB
	SCHEMBL2335645	0.71	ALDH1A1 (0.59)	ALDH1A1MAPTTDP1L3MBTL1POLB
	SCHEMBL30451427	0.71	GPR3 (0.78)	ALDH1A1MAPTTDP1L3MBTL1POLB
	SCHEMBL30077259	0.71	GPR3 (0.78)	ALDH1A1MAPTTDP1L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.