Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076431 | 0.83 | ALDH1A1 (0.59) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL15143214 | 0.83 | HSD17B10 (0.67) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL31123647 | 0.81 | L3MBTL1 (0.58) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL11274332 | 0.81 | L3MBTL1 (0.58) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL156281 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL10360804 | 0.81 | ALDH1A1 (0.77) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL70322 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL27663596 | 0.81 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRHSD17B10POLB | |
| SCHEMBL16771555 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAKDM4EHPGDCA1 | |
| SCHEMBL4215184 | 0.79 | ALDH1A1 (0.54) | ALDH1A1LMNATSHRHIF1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625505-B1 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-10-28 | — | — | EP | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |