Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8731674 | 0.80 | LMNA (0.54) | MAPTACHECYP2D6MEN1KMT2A | |
| SCHEMBL8730081 | 0.80 | TBXA2R (0.45) | MAPTL3MBTL1ACHECYP2D6MEN1 | |
| SCHEMBL8728445 | 0.79 | TBXA2R (0.57) | MEN1KMT2AALDH1A1TBXA2R | |
| SCHEMBL8757978 | 0.78 | TBXA2R (0.49) | MAPTACHECYP2D6MEN1KMT2A | |
| SCHEMBL8982166 | 0.77 | CYP3A4 (0.41) | MAPTL3MBTL1ACHECYP2D6MEN1 | |
| SCHEMBL8728457 | 0.75 | ACACB (0.50) | HIF1A | |
| SCHEMBL27266951 | 0.72 | CA1 (0.61) | ACHECA1CA2TSHRPSEN1 | |
| SCHEMBL27574117 | 0.72 | MAPT (0.58) | MAPTMEN1KMT2ATP53LMNA | |
| SCHEMBL27830337 | 0.72 | MGLL (0.60) | ATMMAPTTP53CYP3A4TSHR | |
| SCHEMBL14669087 | 0.72 | LMNA (0.52) | MAPTACHECYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |