Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070134 | 0.80 | POLB (0.36) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL302524 | 0.72 | — | — | |
| SCHEMBL8585126 | 0.72 | MAPK1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL165897 | 0.70 | — | — | |
| SCHEMBL15398254 | 0.70 | ALDH1A1 (0.38) | PARP1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL8531926 | 0.69 | ALDH1A1 (0.38) | NNMTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24555295 | 0.69 | CYP4F2 (0.38) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL186634 | 0.69 | — | — | |
| SCHEMBL31281659 | 0.68 | — | — | |
| SCHEMBL848821 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998046683-A1 | COATING COMPOSITIONS COMPRISING BUSOXINONE | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-10-22 | — | — | WO | disclosed |