Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20166486 | 0.75 | CRBN (0.45) | — | |
| SCHEMBL21627721 | 0.73 | — | — | |
| SCHEMBL22470021 | 0.72 | ALDH1A1 (0.33) | CDC7DBF4ALDH1A1TRIM24TRIM33 | |
| SCHEMBL31438389 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL20555875 | 0.69 | CDC7 (0.35) | CDC7DBF4 | |
| SCHEMBL8525180 | 0.68 | CYP2A6 (0.42) | CDC7DBF4ALDH1A1 | |
| SCHEMBL4856995 | 0.67 | — | — | |
| SCHEMBL7290529 | 0.67 | ALDH1A1 (0.34) | ALDH1A1TRIM24TRIM33 | |
| SCHEMBL537099 | 0.67 | ALDH1A1 (0.33) | ALDH1A1TRIM24TRIM33 | |
| SCHEMBL3815762 | 0.67 | TRIM24 (0.40) | ALDH1A1TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619177-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038943-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |