Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20921403 | 0.84 | TSHR (0.48) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL3060638 | 0.84 | L3MBTL1 (0.51) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL3050984 | 0.84 | TSHR (0.48) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL11810361 | 0.81 | KMT2A (0.57) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL8125876 | 0.81 | POLB (0.51) | LMNAL3MBTL1MEN1HPGDKMT2A | |
| SCHEMBL14528939 | 0.81 | L3MBTL1 (0.48) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL9918837 | 0.81 | PYCR1 (0.46) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL7349213 | 0.81 | POLB (0.51) | LMNAL3MBTL1MEN1HPGDKMT2A | |
| SCHEMBL6903563 | 0.81 | POLB (0.51) | LMNAL3MBTL1MEN1HPGDKMT2A | |
| SCHEMBL9918209 | 0.81 | HTT (0.45) | TSHRLMNAL3MBTL1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |