Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077723 | 0.93 | PTGDR2 (0.58) | PTGDR2HTR2CSLC6A4HTR2BHTR6 | |
| SCHEMBL82269 | 0.86 | PTGDR2 (0.61) | PTGDR2SLC6A4PTPN1CCR5ALDH1A1 | |
| SCHEMBL29690396 | 0.86 | PTGDR2 (0.61) | PTGDR2SLC6A4PTPN1CCR5ALDH1A1 | |
| SCHEMBL20539294 | 0.84 | PTGDR2 (0.49) | PTGDR2HTR2CSLC6A4HTR2BHTR6 | |
| SCHEMBL7146459 | 0.83 | PTGES (0.57) | HPGDALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL9074689 | 0.82 | MEN1 (0.54) | HTR2CSLC6A4HTR2BHTR6HPGD | |
| SCHEMBL13580973 | 0.81 | ALDH1A1 (0.46) | PTGDR2HTR2CSLC6A4HTR2BHTR6 | |
| SCHEMBL1558065 | 0.80 | ALDH1A1 (0.71) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9077437 | 0.79 | CYP11B1 (0.54) | HPGDALDH1A1SMN1; SMN2KDM4EPTGES | |
| SCHEMBL2066597 | 0.79 | PTGDR2 (0.64) | PTGDR2CCR5HPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641766-B1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 1998-11-11 | — | — | EP | disclosed |
| US-5495046-A | PSYCHOLOGICAL DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0641766-A1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |