Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | GPR17 | Q13304 | 4/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873048 | 1.00 | EGFR (0.60) | EGFRGPR17P2RY2GAAMAPT | |
| SCHEMBL15124434 | 0.87 | EGFR (0.47) | EGFRGPR17P2RY2GAAMAPT | |
| SCHEMBL15124435 | 0.87 | EGFR (0.47) | EGFRGPR17P2RY2GAAMAPT | |
| SCHEMBL15124758 | 0.87 | EGFR (0.47) | EGFRGPR17P2RY2GAAMAPT | |
| SCHEMBL670522 | 0.78 | CES2 (0.54) | KMT2AMEN1RAB9A | |
| SCHEMBL16740929 | 0.78 | CES2 (0.54) | KMT2AMEN1RAB9A | |
| SCHEMBL28680003 | 0.78 | GAA (0.60) | GPR17P2RY2GAAMAPTG6PD | |
| SCHEMBL670521 | 0.78 | CES2 (0.54) | KMT2AMEN1RAB9A | |
| SCHEMBL12393864 | 0.78 | CES2 (0.54) | KMT2AMEN1RAB9A | |
| SCHEMBL4648365 | 0.78 | MAOB (0.56) | GPR17P2RY2GAAMAPTG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552219-B2 | Process for preparing L-phenyl-3-dimethylaminopropane derivative | IND-SWIFT LABORATORIES LIMITED (IN) | 2013-10-08 | — | — | US | disclosed |
| EP-2619174-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | Ind-Swift Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| US-20130190522-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2013-07-25 | — | — | US | disclosed |
| WO-2012038974-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190522-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | CYP3A43, UGT1A1, UGT1A7 | EGFR 1867/4885GPR17 3666/4885P2RY2 3200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.