Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | AGXT | P21549 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8730722 | 1.00 | TP53 (0.38) | TP53LMNACYP3A4TSHRKDM4E | |
| SCHEMBL8728174 | 1.00 | TP53 (0.38) | TP53LMNACYP3A4TSHRKDM4E | |
| SCHEMBL8728176 | 1.00 | TP53 (0.38) | TP53LMNACYP3A4TSHRKDM4E | |
| SCHEMBL8725288 | 0.85 | LMNA (0.39) | TP53LMNACYP3A4TSHRKDM4E | |
| SCHEMBL8725284 | 0.85 | LMNA (0.39) | TP53LMNACYP3A4TSHRKDM4E | |
| SCHEMBL8727620 | 0.85 | LMNA (0.39) | TP53LMNACYP3A4TSHRKDM4E | |
| SCHEMBL8727628 | 0.85 | LMNA (0.39) | TP53LMNACYP3A4TSHRKDM4E | |
| SCHEMBL8725518 | 0.84 | LMNA (0.36) | TP53LMNACYP3A4TSHRKDM4E | |
| SCHEMBL8725521 | 0.84 | LMNA (0.36) | TP53LMNACYP3A4TSHRKDM4E | |
| SCHEMBL8730749 | 0.84 | LMNA (0.36) | TP53LMNACYP3A4TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882695-A1 | BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY | CHISSO CORPORATION (JP) | 1998-12-09 | — | — | EP | disclosed |