SCHEMBL8730749

SCHEMBL8730749

C=CCCOCc1ccc(-c2ccc(C=CC)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
ALOX5 P09917 3/20 0.33
NAAA Q02083 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
CNR2 P34972 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
MET P08581 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8725518 1.00 LMNA (0.36) LMNATP53CYP3A4TSHRKDM4E
SCHEMBL8730743 1.00 LMNA (0.36) LMNATP53CYP3A4TSHRKDM4E
SCHEMBL8725521 1.00 LMNA (0.36) LMNATP53CYP3A4TSHRKDM4E
SCHEMBL8727489 0.91 NAAA (0.36) LMNATP53CYP3A4TSHRKDM4E
SCHEMBL8727487 0.91 NAAA (0.36) LMNATP53CYP3A4TSHRKDM4E
SCHEMBL8732328 0.91 NAAA (0.36) LMNATP53CYP3A4TSHRKDM4E
SCHEMBL8732332 0.91 NAAA (0.36) LMNATP53CYP3A4TSHRKDM4E
SCHEMBL8728447 0.90 L3MBTL1 (0.40) LMNATP53CYP3A4TSHRKDM4E
SCHEMBL8732600 0.86 LMNA (0.37) LMNATP53CYP3A4TSHRKDM4E
SCHEMBL8730531 0.86 LMNA (0.37) LMNATP53CYP3A4TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882695-A1 BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY CHISSO CORPORATION (JP) 1998-12-09 EP disclosed