Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.41 |
| ▸ | GLRB | P48167 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392120 | 0.78 | TDP1 (0.48) | L3MBTL1TDP1NOTUMMEN1KMT2A | |
| SCHEMBL4627938 | 0.76 | TSHR (0.46) | L3MBTL1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL28630164 | 0.75 | GLRA3 (0.47) | GLRA3GLRBL3MBTL1TDP1NOTUM | |
| SCHEMBL8936223 | 0.75 | GABRA1 (0.35) | GLRA3GLRBTDP1LMNAALDH1A1 | |
| Salycilic Acid SCHEMBL1457176 | 0.74 | GLRA3 (0.60) | GLRA3GLRBL3MBTL1TDP1KMT2A | |
| SCHEMBL4734822 | 0.74 | KDM4E (0.50) | GLRA3GLRBTDP1NR1H4KMT2A | |
| Salycilic Acid SCHEMBL29623842 | 0.74 | GLRA3 (0.60) | GLRA3GLRBL3MBTL1TDP1KMT2A | |
| SCHEMBL7065132 | 0.73 | GLRA3 (0.46) | GLRA3GLRBL3MBTL1NOTUMMEN1 | |
| SCHEMBL14989129 | 0.73 | GLRA3 (0.46) | GLRA3GLRBL3MBTL1NOTUMMEN1 | |
| SCHEMBL5483192 | 0.72 | RXRB (0.39) | GLRA3GLRBL3MBTL1TDP1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706987-B1 | Process for preparing alkylated aromatic carboxylic acids and carboxylic acid halogenides | CIBA GEIGY AG (CH) | 1998-06-03 | — | — | EP | disclosed |