Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449005 | 0.88 | LMNA (0.49) | PTPN11RARBNPC1LMNANFKB1 | |
| SCHEMBL9406307 | 0.88 | NPC1 (0.57) | PTPN11RARBNPC1LMNANFKB1 | |
| SCHEMBL9457633 | 0.88 | NPC1 (0.57) | PTPN11RARBNPC1LMNANFKB1 | |
| SCHEMBL9406028 | 0.88 | NPC1 (0.57) | PTPN11RARBNPC1LMNANFKB1 | |
| SCHEMBL9477526 | 0.88 | NPC1 (0.57) | PTPN11RARBNPC1LMNANFKB1 | |
| SCHEMBL9406219 | 0.88 | NPC1 (0.57) | PTPN11RARBNPC1LMNANFKB1 | |
| SCHEMBL8729949 | 0.88 | THRA (0.44) | PTPN11THRATHRBRARBNPC1 | |
| SCHEMBL12741903 | 0.87 | THRA (0.49) | PTPN11THRATHRBRARBNPC1 | |
| SCHEMBL12741905 | 0.87 | THRA (0.49) | PTPN11THRATHRBRARBNPC1 | |
| SCHEMBL12741920 | 0.87 | THRA (0.49) | PTPN11THRATHRBRARBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703955-B1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | SECR DEFENCE BRIT (GB) | 1998-11-11 | — | — | EP | disclosed |