Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.38 |
| ▸ | HTR2A | P28223 | 6/20 | 0.38 |
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | HTR2B | P41595 | 6/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8730981 | 1.00 | SIGMAR1 (0.38) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL8730975 | 1.00 | SIGMAR1 (0.38) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL8730970 | 1.00 | SIGMAR1 (0.38) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL8728236 | 0.85 | GPR84 (0.32) | SIGMAR1HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL8728232 | 0.85 | GPR84 (0.32) | SIGMAR1HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL8728238 | 0.85 | GPR84 (0.32) | SIGMAR1HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL8728229 | 0.85 | GPR84 (0.32) | SIGMAR1HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL8730401 | 0.85 | SPHK1 (0.38) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL8730391 | 0.85 | SPHK1 (0.38) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL8730388 | 0.85 | SPHK1 (0.38) | SIGMAR1HTR2AHTR2CHTR2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882695-A1 | BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY | CHISSO CORPORATION (JP) | 1998-12-09 | — | — | EP | disclosed |