Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.59 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.59 |
| ▸ | STS | P08842 | 6/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885904 | 1.00 | ALDH1A1 (0.68) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL4595623 | 1.00 | ALDH1A1 (0.68) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL194303 | 1.00 | ALDH1A1 (0.68) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL1367226 | 1.00 | ALDH1A1 (0.68) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL7536250 | 1.00 | ALDH1A1 (0.68) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| Padimate A SCHEMBL15372 | 0.98 | ALDH1A1 (0.65) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| Padimate A SCHEMBL28088966 | 0.97 | ALDH1A1 (0.63) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| Nitrous Acid SCHEMBL27509831 | 0.94 | ALDH1A1 (0.61) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL357704 | 0.94 | LMNA (0.68) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL5491979 | 0.94 | ALDH1A1 (0.59) | ALDH1A1NPC1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9222051-B2 | Lubricating composition with improved TBN retention | THE LUBRIZOL CORPORATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-20140187458-A1 | Lubricating Composition With Improved TBN Retention | THE LUBRIZOL CORPORATION (US) | 2014-07-03 | — | — | US | disclosed |
| US-20130281336-A1 | Aminobenzoic Acid Derivatives | THE LUBRIZOL CORPORATION (US) | 2013-10-24 | — | — | US | disclosed |
| EP-2619293-A1 | AMINOBENZOIC ACID DERIVATIVES | The Lubrizol Corporation (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012166781-A1 | LUBRICATING COMPOSITION WITH IMPROVED TBN RETENTION | THE LUBRIZOL CORPORATION (US) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012040021-A1 | AMINOBENZOIC ACID DERIVATIVES | THE LUBRIZOL CORPORATION (US) | 2012-03-29 | — | — | WO | disclosed |