Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955716 | 0.88 | ALDH1A1 (0.48) | ALDH1A1HTTKMT2AMEN1POLB | |
| SCHEMBL7955761 | 0.88 | ALDH1A1 (0.48) | ALDH1A1HTTKMT2AMEN1POLB | |
| SCHEMBL7067318 | 0.79 | AR (0.43) | ALDH1A1HTTARKMT2AMEN1 | |
| SCHEMBL7976152 | 0.77 | AR (0.41) | ALDH1A1HTTARKMT2AMEN1 | |
| SCHEMBL7970022 | 0.77 | AR (0.41) | ALDH1A1HTTARKMT2AMEN1 | |
| SCHEMBL5968972 | 0.75 | KMT2A (0.46) | ALDH1A1ARKMT2AMEN1POLB | |
| SCHEMBL5968978 | 0.75 | KMT2A (0.46) | ALDH1A1ARKMT2AMEN1POLB | |
| SCHEMBL9776653 | 0.72 | KMT2A (0.45) | ALDH1A1HTTARKMT2AMEN1 | |
| SCHEMBL8735356 | 0.71 | CYP3A4 (0.46) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL5968974 | 0.70 | KMT2A (0.49) | ALDH1A1HTTARKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816341-A1 | Process for the preparation of chiral succinic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-07 | — | — | EP | claimed |
| EP-0816341-A1 | Process for the preparation of chiral succinic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-07 | — | — | EP | disclosed |