Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046944 | 0.78 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2 | |
| SCHEMBL4219709 | 0.78 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2 | |
| SCHEMBL262278 | 0.78 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2 | |
| SCHEMBL14621091 | 0.78 | CYP1A2 (0.40) | ALOX15CYP2C9ALDH1A1HPGDMAPT | |
| SCHEMBL7954116 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HPGDL3MBTL1MAPTKMT2A | |
| SCHEMBL7954123 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HPGDL3MBTL1MAPTKMT2A | |
| SCHEMBL472159 | 0.74 | ALDH1A1 (0.58) | ALDH1A1HPGDL3MBTL1MAPTKMT2A | |
| SCHEMBL19266744 | 0.74 | KDM4E (0.41) | ALOX15CYP2C9ALDH1A1HPGDMAPT | |
| SCHEMBL14621112 | 0.74 | KDM4E (0.41) | ALOX15CYP2C9ALDH1A1HPGDMAPT | |
| SCHEMBL19088598 | 0.73 | LMNA (0.56) | CYP2C19ALDH1A1L3MBTL1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816341-A1 | Process for the preparation of chiral succinic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-07 | — | — | EP | disclosed |