Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALPL | P05186 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL9270578 | 0.88 | MAPT (0.47) | PDPK1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7925519 | 0.78 | HPGD (0.50) | PDPK1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1770275 | 0.78 | HPGD (0.50) | PDPK1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL12265084 | 0.77 | HPGD (0.47) | PDPK1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27571730 | 0.75 | ALPL (0.48) | PDPK1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL17279716 | 0.74 | NR1H2 (0.62) | ALDH1A1MEN1KMT2ACYP1A2ADORA2A | |
| SCHEMBL12311990 | 0.74 | HPGD (0.54) | PDPK1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9831636 | 0.74 | CDK5 (0.44) | PDPK1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7324860 | 0.73 | ALPL (0.46) | PDPK1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL17280118 | 0.73 | HPGD (0.49) | PDPK1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023191400-A1 | ETHYL PIPERIDINE TRIAZOLO TRIAZINE DERIVATIVES, SYNTHESIS METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF CANCER | 에이치케이이노엔 주식회사 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023191400-A1 | ETHYL PIPERIDINE TRIAZOLO TRIAZINE DERIVATIVES, SYNTHESIS METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF CANCER | 에이치케이이노엔 주식회사 | 2023-10-05 | — | — | WO | disclosed |
| US-5750545-A | EXHIBIT EOSINOPHIL-INHIBITORY ACTION AND LYMPHOCYTE ACTIVATION-INHIBITORY ACTION; USEFUL FOR TREATMENT OF IMMUNE-RELATED DISEASES | THE GREEN CROSS CORPORATION (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0710654-A1 | TRIAZOLE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5380714-A | Adenosine antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-01-10 | — | — | US | disclosed |
| US-5356894-A | Adenosine antagonists | SYNGENTA LIMITED (GB) | 1994-10-18 | — | — | US | disclosed |
| WO-1994014812-A1 | AZOLE DERIVATIVES AS ADENOSINE ANTAGONISTS | ZENECA LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |
| US-5290776-A | Antagonist of vasodilation activity of adenosine | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1994-03-01 | — | — | US | disclosed |
| US-5270311-A | [1,2,4]-Triazolo[1,5-a]and pyrazolo[2,3-a][1,3,5]triazine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |
| US-5246932-A | Adenosine antagonist such as vasodilation | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-21 | — | — | US | disclosed |
| EP-0544443-A1 | Azole derivatives as adenosine antagonists | ZENECA LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| EP-0515107-A2 | Azolo (1,3,5) triazines as adenosine antagonists | ZENECA LIMITED (GB) | 1992-11-25 | — | — | EP | disclosed |
| EP-0515108-A2 | Azolo (1,3,5) triazines as adenosine antagonists | ZENECA LIMITED (GB) | 1992-11-25 | — | — | EP | disclosed |
| CN-1056879-A | Pyrrole derivative and preparation method thereof | ICI PLC (GB) | 1991-12-11 | — | — | CN | disclosed |
| EP-0459702-A1 | Azole Derivatives | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |