Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831636 | 0.82 | CDK5 (0.44) | ALPLLMNAPDPK1ADORA2AADORA1 | |
| SCHEMBL625453 | 0.77 | ALDH1A1 (0.47) | LMNAADORA2AADORA1ADORA2BALDH1A1 | |
| SCHEMBL7326483 | 0.77 | ALPL (0.42) | ALPLLMNAPDPK1ADORA2AADORA1 | |
| SCHEMBL10713674 | 0.74 | PDPK1 (0.43) | ALPLLMNAPDPK1ADORA2AADORA1 | |
| SCHEMBL10715022 | 0.74 | MAPT (0.45) | ALPLLMNAPDPK1ADORA2AADORA1 | |
| SCHEMBL19716277 | 0.73 | ALPL (0.46) | ALPLLMNAPDPK1ADORA2AADORA1 | |
| SCHEMBL10713001 | 0.73 | LMNA (0.49) | ALPLLMNAALDH1A1HPGDRAB9A | |
| SCHEMBL29722736 | 0.73 | HPGD (0.61) | PDPK1ADORA2AADORA1ADORA2BALDH1A1 | |
| SCHEMBL26905289 | 0.73 | HPGD (0.61) | PDPK1ADORA2AADORA1ADORA2BALDH1A1 | |
| SCHEMBL8731561 | 0.73 | PDPK1 (0.54) | ALPLLMNAPDPK1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831013-A | BENZODIAZEPINE RECEPTOR ANTAGONISTS | CIBA-GEIGY CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| WO-1988002370-A1 | 2-SUBSTITUTED-E-FUSED-[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINES PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | CIBA-GEIGY AG (CH) | 1988-04-07 | — | — | WO | disclosed |
| EP-0263071-A1 | 2-Substituted-e-fused-[1,2,4]-triazolo[1,5-c] pyrimidines, pharmaceutical compositions, and uses thereof | CIBA-GEIGY AG (CH) | 1988-04-06 | — | — | EP | disclosed |