Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 10/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733551 | 0.90 | TBXA2R (0.61) | TBXA2RMEN1KMT2AALDH1A1 | |
| SCHEMBL8734674 | 0.89 | AKR1C3 (0.49) | TBXA2RMEN1KMT2AALDH1A1PKM | |
| SCHEMBL8730079 | 0.85 | TBXA2R (0.61) | TBXA2RGBA1POLBMEN1KMT2A | |
| SCHEMBL8733698 | 0.82 | TBXA2R (0.59) | TBXA2RMEN1KMT2AALDH1A1 | |
| SCHEMBL8982158 | 0.81 | TBXA2R (0.57) | TBXA2RGBA1POLBALDH1A1 | |
| SCHEMBL8731665 | 0.81 | TBXA2R (0.57) | TBXA2RMEN1KMT2AALDH1A1 | |
| SCHEMBL8733700 | 0.81 | TBXA2R (0.62) | TBXA2RMEN1KMT2A | |
| SCHEMBL8730097 | 0.78 | TBXA2R (0.59) | TBXA2RMEN1KMT2A | |
| SCHEMBL8730153 | 0.78 | TBXA2R (0.46) | TBXA2RPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL8982185 | 0.77 | TBXA2R (0.58) | TBXA2RMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589037-B1 | INDIAN DERIVATIVE AND THROMBOXANE ANTAGONIST CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-05-29 | — | — | EP | disclosed |
| US-5409956-A | A sulfonylaminoalkylindan carboxylic acid or ester for treating thrombosis, vasospasm or asthma | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0589037-A1 | INDIAN DERIVATIVE AND THROMBOXANE ANTAGONIST CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-30 | — | — | EP | disclosed |