Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735878 | 0.90 | MAPT (0.45) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL8733661 | 0.90 | KDM4E (0.42) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL8734012 | 0.81 | KDM4E (0.44) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL8736433 | 0.80 | TOP1 (0.50) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL8734028 | 0.80 | KDM4E (0.45) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL8735884 | 0.80 | KDM4E (0.45) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL8879095 | 0.78 | KDM4E (0.48) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL8733517 | 0.75 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL8878202 | 0.75 | KDM4E (0.44) | SMN1; SMN2KDM4EADRA2BMAPK1ALDH1A1 | |
| SCHEMBL27330797 | 0.75 | KDM4E (0.44) | KDM4EADRA2BMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |