Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736433 | 0.92 | TOP1 (0.50) | KDM4EALDH1A1TOP1NPC1RAB9A | |
| SCHEMBL8734028 | 0.92 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10TOP1 | |
| SCHEMBL8735884 | 0.91 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10TOP1 | |
| SCHEMBL8733661 | 0.90 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10TOP1 | |
| SCHEMBL8736445 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8733875 | 0.82 | RAB9A (0.41) | ALDH1A1HSD17B10NPC1RAB9ALMNA | |
| SCHEMBL8735561 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8732189 | 0.81 | NPC1 (0.45) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL8735878 | 0.80 | MAPT (0.45) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL27348555 | 0.79 | PIK3CD (0.47) | KDM4EALDH1A1HPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | claimed |
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |