SCHEMBL8732641

SCHEMBL8732641

CC1=Cc2c(-c3ccccc3)cccc2C1[Zr]C1C(C)=Cc2c(-c3ccccc3)cccc21.C[SiH2]OC(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7629353 0.92
SCHEMBL7626672 0.90
SCHEMBL5678404 0.87 PDCD1 (0.33)
SCHEMBL31253552 0.85 PDCD1 (0.35)
SCHEMBL3404398 0.85 PDCD1 (0.35)
SCHEMBL8732742 0.83 PDCD1 (0.30)
Hydrochloric Acid SCHEMBL7943365 0.83 PDCD1 (0.33)
SCHEMBL6531333 0.80 PDCD1 (0.33)
SCHEMBL7983533 0.79 PDCD1 (0.34)
SCHEMBL14905713 0.79 NPC1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0858462-A1 SUPPORTABLE BISCYCLOPENTADIENYL METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1998-08-19 EP disclosed
WO-1997015582-A1 SUPPORTABLE BISCYCLOPENTADIENYL METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-05-01 WO disclosed