Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | QPCT | Q16769 | 4/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | WNT3A | P56704 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperonylic Acid SCHEMBL8733052 | 0.90 | ALDH1A1 (0.63) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL5946 | 0.84 | RAB9A (0.71) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28553547 | 0.83 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL28108857 | 0.83 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL27310663 | 0.83 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL2725220 | 0.83 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| Methylamine SCHEMBL3153881 | 0.80 | RAB9A (0.65) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| Piperonylic Acid SCHEMBL31119409 | 0.80 | ALDH1A1 (1.00) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| Piperonylic Acid SCHEMBL142318 | 0.80 | ALDH1A1 (1.00) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| Piperonylic Acid SCHEMBL3946119 | 0.80 | ALDH1A1 (1.00) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |