Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10714708 | 0.82 | KMT2A (0.42) | LMNAFFAR1NPC1MAPK1 | |
| SCHEMBL13385106 | 0.82 | LMNA (0.68) | LMNAMAOAPTGS1MTNR1AMTNR1B | |
| SCHEMBL27956310 | 0.80 | LMNA (0.34) | LMNAMAOAPTGS1MTNR1AMTNR1B | |
| SCHEMBL5251046 | 0.80 | LMNA (0.52) | LMNAMAOAPTGS1MTNR1AMTNR1B | |
| SCHEMBL96350 | 0.79 | LMNA (0.59) | LMNAMAOAPTGS1MTNR1AMTNR1B | |
| SCHEMBL96547 | 0.77 | LMNA (0.57) | LMNAMAOAPTGS1MTNR1AMTNR1B | |
| SCHEMBL8651047 | 0.76 | LMNA (0.52) | LMNAMTNR1AMTNR1BCYP2D6ADRB2 | |
| SCHEMBL2500159 | 0.76 | FFAR1 (0.61) | LMNAMAOAPTGS1MTNR1AMTNR1B | |
| SCHEMBL28294103 | 0.76 | FFAR1 (0.61) | LMNAMAOAPTGS1MTNR1AMTNR1B | |
| SCHEMBL2790730 | 0.76 | LMNA (0.55) | LMNAMAOAPTGS1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0155973-B1 | HYDROCARBYLOXY ALKANALS, ORGANOLEPTIC USES THEREOF AND PROCESSORS FOR PREPARING SAME | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1988-12-14 | — | — | EP | disclosed |
| US-4556746-A | ORGANOLEPTIC | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1985-12-03 | — | — | US | disclosed |