Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | GPR88 | Q9GZN0 | 5/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | SCN4A | P35499 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294103 | 1.00 | FFAR1 (0.61) | FFAR1LMNAMAOAPTGS1GPR88 | |
| Anisole SCHEMBL28132815 | 0.92 | FFAR1 (0.55) | FFAR1LMNAMAOAPTGS1GPR88 | |
| SCHEMBL4976110 | 0.92 | FFAR1 (0.59) | FFAR1LMNAMAOAPTGS1GPR88 | |
| SCHEMBL13385106 | 0.89 | LMNA (0.68) | FFAR1LMNAMAOAPTGS1MTNR1A | |
| SCHEMBL17138170 | 0.85 | GPBAR1 (0.60) | FFAR1LMNAGPBAR1MTNR1AMTNR1B | |
| SCHEMBL27330236 | 0.83 | LMNA (0.57) | LMNAMAOAPTGS1GPR88 | |
| SCHEMBL10705795 | 0.83 | FFAR1 (0.53) | FFAR1LMNAGPR88GPBAR1CYP2D6 | |
| SCHEMBL10705801 | 0.83 | FFAR1 (0.53) | FFAR1LMNAGPR88GPBAR1CYP2D6 | |
| SCHEMBL9640139 | 0.82 | FFAR1 (0.65) | FFAR1GPR88 | |
| SCHEMBL9639286 | 0.81 | FFAR1 (0.52) | FFAR1LMNAMAOAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124332-A | AN ENZYME INHIBITOR FOR THE TREATMENT OR PROPHYLAXIS OF TISSUE BREAKDOWN, FOR EXAMPLE RHEUMATOID ARTHRITIS, OSTEOPOROSIS, PERIODONTITIS, GINGIVITIS, CORNEAL EPIDERMAL OR GASTRIC ULCERATION, AND TUMOR, MULTIPLE SCLEROSIS | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2000-09-26 | — | — | US | claimed |
| US-6022898-A | ALPHA-SULFONYLAMINO-SUBSTITUTED HYDROXAMIC ACIDS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-02-08 | — | — | US | claimed |
| EP-0766665-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-07-28 | — | — | EP | claimed |
| EP-0766665-A2 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-04-09 | — | — | EP | claimed |
| EP-0766664-A2 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-04-09 | — | — | EP | claimed |
| WO-1995035275-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-12-28 | — | — | WO | claimed |
| WO-1995035276-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-12-28 | — | — | WO | claimed |
| US-10932995-B2 | Dental composition with high E-modulus | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-03-02 | — | — | US | disclosed |
| US-20200360241-A1 | DENTAL COMPOSITION WITH HIGH E-MODULUS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2020-11-19 | — | — | US | disclosed |
| CN-109804481-A | Organic photodetector | 默克专利有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-109791987-A | Organic semiconductor compound | 默克专利有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109790176-A | Organic semiconductor compound | 默克专利有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-108570420-A | The recombinant production system of aromatic molecules | RHO可再生股份有限公司 | 2018-09-25 | — | — | CN | disclosed |
| CN-1141441-A | Optical device for frequency conversion | DU PONT (US) | 1997-01-29 | — | — | CN | disclosed |
| WO-1995035276-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-12-28 | — | — | WO | disclosed |
| WO-1995035275-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-12-28 | — | — | WO | disclosed |
| CN-1054587-A | Fluorinated sulfones/ketones for nonlinear optics | DU PONT (US) | 1991-09-18 | — | — | CN | disclosed |
| EP-0275007-A2 | Process for the preparation of highly molecular, optionally branched polyarylene sulfides | BAYER AG (DE) | 1988-07-20 | — | — | EP | disclosed |
| US-4393241-A | Synthesis of alkoxy and phenoxy substituted aryl sulfides | CELANESE CORPORATION (US) | 1983-07-12 | — | — | US | disclosed |
| EP-0006718-B1 | 1.2.4-TRIAZOLIDINE-3.5-DIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10932995-B2 | Dental composition with high E-modulus | ELL, BRD4, FHIT | FFAR1 3589/4885LMNA 2301/4885MAOA 394/4885 |
| US-20200360241-A1 | DENTAL COMPOSITION WITH HIGH E-MODULUS | ELL, BRD4, FHIT | FFAR1 3589/4885LMNA 2301/4885MAOA 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.