SCHEMBL873317

SCHEMBL873317

CCCCCCCCC(=O)OC(C)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.57
MAPK1 P28482 5/20 0.54
MAPT P10636 4/20 0.54
ALDH1A1 P00352 2/20 0.52
ASAH1 Q13510 2/20 0.52
ACER2 Q5QJU3 1/20 0.52
TLR2 O60603 3/20 0.52
GMNN O75496 3/20 0.48
NPSR1 Q6W5P4 3/20 0.48
CYP1A2 P05177 2/20 0.48
MEN1 O00255 2/20 0.48
HSP90AA1 P07900 2/20 0.48
BLM P54132 2/20 0.48
KMT2A Q03164 2/20 0.48
NR1H4 Q96RI1 2/20 0.48
TP53 P04637 1/20 0.48
CYP2C9 P11712 1/20 0.48
TSHR P16473 1/20 0.48
HIF1A Q16665 1/20 0.48
PRKCA P17252 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28382858 1.00 LMNA (0.57) LMNAMAPK1MAPTALDH1A1ASAH1
SCHEMBL28377399 1.00 LMNA (0.57) LMNAMAPK1MAPTALDH1A1ASAH1
SCHEMBL8644855 1.00 LMNA (0.57) LMNAMAPK1MAPTALDH1A1ASAH1
SCHEMBL873937 1.00 LMNA (0.57) LMNAMAPK1MAPTALDH1A1ASAH1
SCHEMBL17683986 1.00 LMNA (0.57) LMNAMAPK1MAPTALDH1A1ASAH1
SCHEMBL8642007 1.00 LMNA (0.57) LMNAMAPK1MAPTALDH1A1ASAH1
SCHEMBL8638934 1.00 LMNA (0.57) LMNAMAPK1MAPTALDH1A1ASAH1
SCHEMBL10766988 1.00 LMNA (0.57) LMNAMAPK1MAPTALDH1A1ASAH1
SCHEMBL8638133 1.00 LMNA (0.57) LMNAMAPK1MAPTALDH1A1ASAH1
SCHEMBL28379934 1.00 LMNA (0.57) LMNAMAPK1MAPTALDH1A1ASAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10006151-B2 Polyurethane fiber TORAY OPELONTEX CO., LTD. (JP) 2018-06-26 US disclosed
EP-2947185-B1 POLYURETHANE FIBER AND ITS USE TORAY OPELONTEX CO LTD (JP) 2018-02-28 EP disclosed
US-9358191-B2 Deodorant composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2016-06-07 US disclosed
US-20160002827-A1 POLYURETHANE FIBER TORAY OPELONTEX CO., LTD. (JP) 2016-01-07 US disclosed
EP-2947185-A1 POLYURETHANE FIBER Toray Opelontex Co., Ltd (JP) 2015-11-25 EP disclosed
US-8961946-B2 Hair processing agent and method for permanent waving hair SHOWA DENKO K.K. (JP) 2015-02-24 US disclosed
US-20140271522-A1 DEODORANT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-09-18 US disclosed
US-8778320-B2 Deodorant composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-07-15 US disclosed
EP-1561476-B1 DEODORANT COMPOSITION TAKASAGO PERFUMERY CO LTD (JP) 2014-02-12 EP disclosed
EP-2618856-A1 DEODORANT COMPOSITION FOR SULFIDES Takasago International Corporation (JP) 2013-07-31 EP disclosed
US-20130136713-A1 DEODORANT COMPOSITION FOR SULFIDES TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-05-30 US disclosed
WO-2012039516-A1 DEODORANT COMPOSITION FOR SULFIDES TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-03-29 WO disclosed
US-20090087401-A1 DEODORANT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-04-02 US disclosed
US-20080085251-A1 even at a neutral to weakly acidic pH; a lactone or lactam having a mercapto group; with thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine; RESONAC CORPORATION (JP) 2008-04-10 US disclosed
EP-1827370-A1 HAIR PROCESSING AGENT AND METHOD FOR PERMANENT WAVING HAIR Showa Denko K.K. (JP) 2007-09-05 EP disclosed
US-20060165622-A1 Deodorant composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-07-27 US disclosed
WO-2006068276-A1 HAIR PROCESSING AGENT AND METHOD FOR PERMANENT WAVING HAIR SHOWA DENKO K.K. (JP) 2006-06-29 WO disclosed
EP-1561476-A1 DEODORANT COMPOSITION Takasago International Corporation (JP) 2005-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080085251-A1 even at a neutral to weakly acidic pH; a lactone or lactam having a mercapto group; with thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine; TST, CYSLTR1, CYSLTR2 LMNA 4594/4885MAPK1 3014/4885MAPT 4300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.