Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728179 | 0.92 | SIRT2 (0.47) | BIRC2ITGB3ITGA2BSIRT2SIRT1 | |
| SCHEMBL5604046 | 0.88 | CA12 (0.56) | BIRC2ITGB3ITGA2BCA12CA2 | |
| SCHEMBL8733195 | 0.84 | BIRC2 (0.45) | BIRC2SIRT2SIRT1SIRT3CA12 | |
| SCHEMBL16938448 | 0.82 | CA2 (0.48) | ITGB3ITGA2BCA12CA2CA7 | |
| SCHEMBL8734416 | 0.82 | ZDHHC7 (0.50) | BIRC2ITGB3ITGA2BCA2 | |
| SCHEMBL10769571 | 0.81 | ITGB3 (0.50) | ITGB3ITGA2BPTPN1CA2MMP9 | |
| SCHEMBL8734422 | 0.79 | ASAH2 (0.43) | PTPN1MMP1MMP9MMP13 | |
| SCHEMBL4067325 | 0.79 | ITGB3 (0.61) | ITGB3ITGA2BPTPN1POLBMMP9 | |
| SCHEMBL5603960 | 0.79 | ITGB3 (0.61) | ITGB3ITGA2BPTPN1POLBMMP9 | |
| SCHEMBL7622370 | 0.79 | ITGB3 (0.61) | ITGB3ITGA2BPTPN1POLBMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701561-B1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | MENARINI LAB (ES) | 1998-08-19 | — | — | EP | disclosed |