Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855525 | 0.89 | PLK1 (0.53) | PLK1ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL11854099 | 0.85 | DCTPP1 (0.35) | PLK1ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL8855422 | 0.85 | PLK1 (0.50) | PLK1ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL8855447 | 0.82 | CYP3A4 (0.39) | PLK1ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL8855513 | 0.81 | MAPT (0.41) | PLK1ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL8855595 | 0.80 | CYP3A4 (0.37) | PLK1ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL8855402 | 0.80 | PLK1 (0.36) | PLK1ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL8855562 | 0.78 | LMNA (0.49) | PLK1ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL22954616 | 0.78 | PLK1 (0.50) | PLK1ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL29517736 | 0.78 | PLK1 (0.50) | PLK1ALDH1A1TDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821953-A2 | Anticoccidial methods and feedstuffs | ELI LILLY AND COMPANY (US) | 1998-02-04 | — | — | EP | claimed |
| US-5635490-A | ADMINISTERING POLYETHER ANTIBIOTIC AND BENZIMIDAZOLE DERIVATIVE | ELI LILLY AND COMPANY (US) | 1997-06-03 | — | — | US | claimed |
| EP-0616806-A1 | Phenylenediamine or benzimidazole derivatives for treating coccidiosis | ELI LILLY AND COMPANY (US) | 1994-09-28 | — | — | EP | claimed |
| US-3980784-A | Control of animal parasites with benzimidazoles | ELI LILLY AND COMPANY (US) | 1976-09-14 | — | — | US | claimed |
| JP-6305957-A | — | — | None | — | — | JP | disclosed |
| EP-0821953-A2 | Anticoccidial methods and feedstuffs | ELI LILLY AND COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |
| JP-H06305957-A | ANTICOCCIDIOSIS FEED | ELI LILLY & CO | 1994-11-01 | — | — | JP | disclosed |
| EP-0616806-A1 | Phenylenediamine or benzimidazole derivatives for treating coccidiosis | ELI LILLY AND COMPANY (US) | 1994-09-28 | — | — | EP | disclosed |
| US-4265901-A | HERBICIDES, INSECTICIDES, PARASITICIDES | ELI LILLY AND COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-3980784-A | Control of animal parasites with benzimidazoles | ELI LILLY AND COMPANY (US) | 1976-09-14 | — | — | US | disclosed |