SCHEMBL8733359

SCHEMBL8733359

Cc1cc2c(cc1C)C(C)(C)[C@@H](C)[C@H](C)C2(C)C

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9080035 1.00 RXRA (0.36) RXRA
SCHEMBL9079442 1.00 RXRA (0.36) RXRA
SCHEMBL9079436 1.00 RXRA (0.36) RXRA
SCHEMBL16318604 0.83 RXRA (0.47) RXRA
SCHEMBL5611209 0.79 GRIA1 (0.39) RXRA
SCHEMBL8733323 0.79 TSHR (0.33)
SCHEMBL30292091 0.79 GRIA1 (0.39) RXRA
SCHEMBL16194802 0.79 SHBG (0.36) RXRA
SCHEMBL30754351 0.79 GRIA1 (0.39) RXRA
SCHEMBL29369649 0.79 GRIA1 (0.39) RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5442124-A Process for the preparation of novel aromatic compounds FIRMENICH SA (CH) 1995-08-15 US claimed
EP-0405427-B1 Aromatic compounds, process for their preparation and their use as perfuming ingredients FIRMENICH & CIE (CH) 1995-03-29 EP claimed
US-5324875-A Musk odor FIRMENICH SA (CH) 1994-06-28 US claimed
EP-0664286-B1 Tetralin nitriles, their use as ingredients for perfumes and oxime intermediates for their preparation FIRMENICH & CIE (CH) 1998-04-22 EP disclosed
US-5559272-A Aromatic compounds FIRMENICH S.A. (CH) 1996-09-24 US disclosed
US-5521151-A Tetralinic nitriles, their use as perfuming ingredients and aldehyde intermediates for their preparation FIRMENICH S.A. (CH) 1996-05-28 US disclosed
US-5442124-A Process for the preparation of novel aromatic compounds FIRMENICH SA (CH) 1995-08-15 US disclosed
EP-0664286-A1 Tetralin nitriles, their use as ingredients for perfumes and oxime intermediates for their preparation FIRMENICH SA (CH) 1995-07-26 EP disclosed
US-5324875-A Musk odor FIRMENICH SA (CH) 1994-06-28 US disclosed
US-5185318-A Aromatic compounds, a process for preparation thereof and use of same as perfuming ingredients FIRMENICH S.A. (CH) 1993-02-09 US disclosed
US-5162588-A Muky type odor; colognes, shaving lotions, soaps, bath gels, shampoos, hair care products FIRMENICH S.A. (CH) 1992-11-10 US disclosed