Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Hexanal. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Undecanal SCHEMBL20269232 | 0.98 | TSHR (0.52) | TSHRFAAHTRPV1LMNADGKA | |
| Decanal SCHEMBL19357144 | 0.90 | TSHR (0.50) | TSHRFAAHTRPV1LMNADGKA | |
| Hexanal SCHEMBL18339145 | 0.90 | TSHR (0.52) | TSHRFAAHTRPV1LMNADGKA | |
| Hexanal SCHEMBL10352184 | 0.89 | TSHR (0.60) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| Heptanal SCHEMBL873107 | 0.88 | TSHR (0.55) | TSHRFAAHTRPV1LMNADGKA | |
| Decanal SCHEMBL6949312 | 0.88 | TSHR (0.64) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| Heptanal SCHEMBL1664616 | 0.88 | TSHR (0.64) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| Decanal SCHEMBL598213 | 0.88 | TSHR (0.64) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| Decanal SCHEMBL597465 | 0.88 | TSHR (0.64) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| Hexanal SCHEMBL27935104 | 0.88 | TSHR (0.62) | TSHRFAAHTRPV1LMNADGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12496370-B2 | Freshening compositions comprising controlled release modulators | Arylessence, Inc. (US) | 2025-12-16 | — | — | US | claimed |
| CN-119655487-A | Electronic atomized liquid and preparation method thereof | 东莞市鸿馥生物科技有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-119111761-A | Guava essence and preparation method thereof | 东莞奇易香料有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-117327535-B | Green apple extract, preparation method thereof and essence containing green apple extract | 广东香龙香料有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117327535-A | Green apple extract, preparation method thereof and essence containing green apple extract | 广东香龙香料有限公司 | 2024-01-02 | — | — | CN | claimed |
| US-11806448-B2 | Freshening compositions comprising controlled release modulators | Arylessence, Inc. (US) | 2023-11-07 | — | — | US | claimed |
| CN-116660462-A | Detection method for identifying whether essence is illegally added into rice | 陈克明食品股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-114752441-A | Plum syrup essence and production process thereof | 浙江澳杰生物技术有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-112006323-A | Electronic cigarette oil and preparation method thereof | 深圳雪雾科技有限公司 | 2020-12-01 | — | — | CN | claimed |
| US-20260078079-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES | OSMO LABS PBC (US) | 2026-03-19 | — | — | US | disclosed |
| US-20260069734-A1 | FRESHENING COMPOSITIONS COMPRISING CONTROLLED RELEASE MODULATORS | ARYLESSENCE INC (US) | 2026-03-12 | — | — | US | disclosed |
| CN-119111761-B | Guava essence and preparation method thereof | 东莞奇易香料有限公司 | 2026-02-24 | — | — | CN | disclosed |
| US-20260028554-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES | OSMO LABS PBC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12496370-B2 | Freshening compositions comprising controlled release modulators | Arylessence, Inc. (US) | 2025-12-16 | — | — | US | disclosed |
| CN-1874693-A | Food products containing a fruit component | TAKASAGO PERFUMERY CO LTD (JP) | 2006-12-06 | — | — | CN | disclosed |
| EP-1689256-A1 | FOOD PRODUCTS CONTAINING A FRUIT COMPONENT | Takasago International Corporation (JP) | 2006-08-16 | — | — | EP | disclosed |
| US-20060165622-A1 | Deodorant composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-07-27 | — | — | US | disclosed |
| CN-1732019-A | Deodorant composition | TAKASAGO PERFUMERY CO LTD (JP) | 2006-02-08 | — | — | CN | disclosed |
| EP-1561476-A1 | DEODORANT COMPOSITION | Takasago International Corporation (JP) | 2005-08-10 | — | — | EP | disclosed |
| WO-2005048743-A1 | FOOD PRODUCTS CONTAINING A FRUIT COMPONENT | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028554-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES | TAS2R42, TAS2R4, TAS2R41 | TSHR 2405/4885FAAH 47/4885TRPV1 30/4885 |
| US-20260069734-A1 | FRESHENING COMPOSITIONS COMPRISING CONTROLLED RELEASE MODULATORS | FFAR1, FFAR2, FFAR3 | TSHR 1822/4885FAAH 6/4885TRPV1 19/4885 |
| US-20260078079-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES | CBR1, CBR3, TAS2R1 | TSHR 1119/4885FAAH 420/4885TRPV1 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.