Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8730030 | 0.87 | TBXA2R (0.61) | TBXA2RTSHRALOX15NPY5RGBA1 | |
| SCHEMBL8728448 | 0.84 | TBXA2R (0.71) | TBXA2RALDH1A1GBA1 | |
| SCHEMBL8728445 | 0.81 | TBXA2R (0.57) | TBXA2RALDH1A1NPY5RGBA1 | |
| SCHEMBL8731672 | 0.80 | TBXA2R (0.61) | POLBTBXA2RSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8733707 | 0.80 | TBXA2R (0.53) | TBXA2RTSHRALDH1A1GAALMNA | |
| SCHEMBL11363199 | 0.79 | TSHR (0.75) | POLBTBXA2RTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8982158 | 0.79 | TBXA2R (0.57) | POLBTBXA2RSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8729260 | 0.78 | POLB (0.46) | POLBTSHRSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL8730152 | 0.78 | TBXA2R (0.64) | TBXA2RTSHRALOX15 | |
| SCHEMBL8768150 | 0.76 | ADRB3 (0.44) | POLBTSHRALDH1A1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |