Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522285 | 0.89 | LMNA (0.57) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9525851 | 0.88 | LMNA (0.61) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8734032 | 0.88 | LMNA (0.63) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9525694 | 0.86 | LMNA (0.55) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1699575 | 0.86 | LMNA (0.55) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9525877 | 0.86 | ALDH1A1 (0.59) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9523420 | 0.85 | LMNA (0.53) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9523651 | 0.85 | LMNA (0.55) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10565041 | 0.85 | LMNA (0.59) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9523533 | 0.85 | LMNA (0.59) | LMNAKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0572259-A1 | Aminoquinolone derivatives as anti-HIV agents | UBE INDUSTRIES, LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |