Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233919 | 0.84 | TSHR (0.62) | CA1CA2TSHRMEN1KMT2A | |
| SCHEMBL8450259 | 0.83 | HPGD (0.50) | CA1CA2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29161460 | 0.82 | MAPT (0.60) | CA1CA2TSHRMEN1KMT2A | |
| SCHEMBL28387396 | 0.80 | HCAR2 (0.52) | CA1CA2TSHRMEN1KMT2A | |
| SCHEMBL10638128 | 0.79 | LOXL2 (0.56) | CA1CA2TSHRMEN1KMT2A | |
| SCHEMBL6665979 | 0.77 | LOXL2 (0.66) | CA1CA2TSHRMEN1KMT2A | |
| SCHEMBL6659672 | 0.76 | ALDH1A1 (0.53) | MEN1KMT2ASMN1; SMN2RAB9ALMNA | |
| SCHEMBL6659668 | 0.76 | ALDH1A1 (0.53) | MEN1KMT2ASMN1; SMN2RAB9ALMNA | |
| SCHEMBL8523359 | 0.76 | KMT2A (0.62) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8523361 | 0.76 | KMT2A (0.62) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874826-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024331-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-07-10 | — | — | WO | disclosed |