Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888271 | 0.86 | NPSR1 (0.35) | NPSR1 | |
| SCHEMBL888572 | 0.85 | NPSR1 (0.38) | NPSR1 | |
| SCHEMBL819689 | 0.85 | NPSR1 (0.31) | NPSR1 | |
| SCHEMBL818359 | 0.83 | NPSR1 (0.33) | NPSR1 | |
| SCHEMBL888665 | 0.81 | MMP8 (0.33) | NPSR1 | |
| SCHEMBL888502 | 0.80 | ALDH1A1 (0.34) | NPSR1 | |
| SCHEMBL21206335 | 0.79 | EPHX1 (0.34) | KEAP1NFE2L2KLK7 | |
| SCHEMBL8154154 | 0.76 | CHRM2 (0.35) | — | |
| SCHEMBL8163061 | 0.75 | CHRM2 (0.37) | — | |
| SCHEMBL8736589 | 0.74 | NPSR1 (0.35) | NPSR1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704424-B1 | 3-Alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin | SHOWA DENKO KK (JP) | 1998-12-30 | — | — | EP | claimed |