Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534540 | 0.85 | ALDH1A1 (0.50) | GAALMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1362192 | 0.85 | HPGD (0.68) | ESR1ESR2GAATDP1TSHR | |
| SCHEMBL30523685 | 0.85 | HPGD (0.68) | ESR1ESR2GAATDP1TSHR | |
| SCHEMBL29503757 | 0.82 | KDM4E (0.70) | GAATDP1TSHRNFKB1KDM4E | |
| SCHEMBL28492275 | 0.82 | ESR1 (0.63) | ESR1ESR2GAATDP1TSHR | |
| SCHEMBL1331519 | 0.82 | KDM4E (0.70) | GAATDP1TSHRNFKB1KDM4E | |
| SCHEMBL13176793 | 0.82 | ESR1 (0.53) | ESR1ESR2GAATDP1TSHR | |
| SCHEMBL4023960 | 0.81 | ESR1 (0.61) | ESR1ESR2GAATDP1TSHR | |
| Hydrochloric Acid SCHEMBL28072109 | 0.81 | KDM4E (0.68) | GAATDP1TSHRNFKB1KDM4E | |
| SCHEMBL8736655 | 0.81 | ESR2 (0.52) | ESR1ESR2GAATDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696566-B1 | Process for production of phenyllactic acid derivative | NITTO CHEMICAL INDUSTRY CO LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5684186-A | HYDROGENATION OF A PHENYLPYRUVIC DERIVATIVE | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0696566-A1 | Process for production of phenyllactic acid derivative | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |