Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FABP7 | O15540 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2108892 | 0.79 | TSHR (0.49) | TSHRHTR2AHDAC3HDAC4HDAC7 | |
| SCHEMBL1568272 | 0.76 | TSHR (0.50) | TSHRHTR2AHDAC3HDAC4HDAC7 | |
| SCHEMBL42370 | 0.76 | EGFR (0.51) | TSHRHTR2AHDAC3HDAC4HDAC7 | |
| SCHEMBL8279094 | 0.75 | POLB (0.50) | TSHRHTR2AHDAC3HDAC4HDAC7 | |
| SCHEMBL87863 | 0.75 | HSD17B10 (0.59) | TSHRHTR2AHDAC3HDAC4HDAC7 | |
| SCHEMBL87862 | 0.75 | TSHR (0.49) | TSHRHTR2AHDAC3HDAC4HDAC7 | |
| SCHEMBL8728938 | 0.74 | TSHR (0.45) | TSHRHTR2AHDAC3HDAC4HDAC7 | |
| SCHEMBL458347 | 0.74 | TSHR (0.45) | TSHRHTR2AHDAC3HDAC4HDAC7 | |
| SCHEMBL21758217 | 0.72 | HTR2A (0.50) | TSHRHTR2AMAPTHSD17B10CA1 | |
| SCHEMBL14880206 | 0.72 | HDAC8 (0.53) | TSHRHTR2AHDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839833-A2 | Catalyst systems for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA S.A. (ES) | 1998-05-06 | — | — | EP | disclosed |