Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 15/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8758160 | 0.84 | ACACB (0.47) | ACACB | |
| SCHEMBL8733934 | 0.82 | NAMPT (0.48) | PTPN1 | |
| SCHEMBL8727048 | 0.78 | SLC6A4 (0.43) | ACACB | |
| SCHEMBL8732948 | 0.77 | PTPN1 (0.48) | ACACBITGB3ITGA2BHDAC8BCL2 | |
| SCHEMBL8732292 | 0.76 | ACACB (0.48) | ACACBITGB3ITGA2BHDAC8 | |
| SCHEMBL8729111 | 0.76 | BCL2 (0.48) | ACACBITGB3ITGA2BHDAC8BCL2 | |
| SCHEMBL8732743 | 0.75 | ACACB (0.50) | ACACBITGB3ITGA2BHDAC8 | |
| SCHEMBL19930027 | 0.75 | BCL2 (0.59) | ITGB3ITGA2BHDAC8BCL2PTPN1 | |
| SCHEMBL12532786 | 0.75 | BCL2 (0.59) | ITGB3ITGA2BHDAC8BCL2PTPN1 | |
| SCHEMBL8732428 | 0.75 | HDAC8 (0.53) | ACACBITGB3ITGA2BHDAC8BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |