Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | ABL2 | P42684 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733935 | 1.00 | FBP1 (0.62) | FBP1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7404491 | 0.86 | FBP1 (0.56) | FBP1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8736030 | 0.83 | FBP1 (0.53) | FBP1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8736029 | 0.83 | FBP1 (0.53) | FBP1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL10892988 | 0.81 | FBP1 (0.62) | FBP1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL10892986 | 0.81 | FBP1 (0.62) | FBP1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7557512 | 0.79 | CA2 (0.52) | ALDH1A1LMNAMAPTCYP3A4CYP2C9 | |
| SCHEMBL7139084 | 0.78 | FBP1 (0.68) | FBP1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7139089 | 0.78 | FBP1 (0.68) | FBP1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7139086 | 0.78 | FBP1 (0.68) | FBP1ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874826-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024331-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-07-10 | — | — | WO | disclosed |