Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL27488842 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL3693425 | 1.00 | TDP1 (0.77) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL29873191 | 0.88 | — | — | |
| Propylene Glycol SCHEMBL724028 | 0.88 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL161401 | 0.88 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL15864609 | 0.88 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL7522896 | 0.88 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL3535 | 0.88 | — | — | |
| Propylene Glycol SCHEMBL55583 | 0.88 | — | — | |
| Propylene Glycol SCHEMBL28578 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114479006-B | Structural flame-retardant polyurethane foam material suitable for heat preservation in building of cold storage skiing field | 万华节能科技(烟台)有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-114621154-B | Adduct and preparation method thereof, flame retardant composition and application | 金发科技股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-116554435-A | High-functionality modified flame-retardant isocyanate compound and synthesis method thereof | 万华节能科技(烟台)有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-113771326-B | Production process method of EVA (ethylene vinyl acetate) film for flame-retardant laminated glass | 安徽省阳明达新材料科技有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-114479006-A | Structural flame-retardant polyurethane foam material suitable for heat preservation in refrigeration house ski field building | 万华节能科技(烟台)有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114437311-B | High-flame-retardance low-TVOC low-density spray foam of all-water system | 万华节能科技(烟台)有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-114479006-B | Structural flame-retardant polyurethane foam material suitable for heat preservation in building of cold storage skiing field | 万华节能科技(烟台)有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-114621154-B | Adduct and preparation method thereof, flame retardant composition and application | 金发科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-116554435-A | High-functionality modified flame-retardant isocyanate compound and synthesis method thereof | 万华节能科技(烟台)有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-114621154-A | Adduct and preparation method thereof, flame-retardant composition and application | 金发科技股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114479006-A | Structural flame-retardant polyurethane foam material suitable for heat preservation in refrigeration house ski field building | 万华节能科技(烟台)有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114437311-A | Full-water-system high-flame-retardant low-TVOC low-density spray foam | 万华节能科技(烟台)有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-0769014-B1 | PROCESS FOR PREPARING N-PHOSPHONOMETHYLAMINO CARBOXYLIC ACIDS | MONSANTO CO (US) | 1998-10-21 | — | — | EP | disclosed |
| EP-0769014-A1 | PROCESS FOR PREPARING N-PHOSPHONOMETHYLAMINO CARBOXYLIC ACIDS | MONSANTO COMPANY (US) | 1997-04-23 | — | — | EP | disclosed |
| US-5602276-A | REACTING AN ALKANOLAMINE, FORMALDEHYDE AND DIALKYL PHOSPHITE | MONSANTO COMPANY (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996001266-A1 | PROCESS FOR PREPARING N-PHOSPHONOMETHYLAMINO CARBOXYLIC ACIDS | MONSANTO COMPANY (US) | 1996-01-18 | — | — | WO | disclosed |