Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.38 |
| ▸ | TOP1 | P11387 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733567 | 0.88 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8735563 | 0.88 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8736415 | 0.84 | CHRM1 (0.53) | TOP1CHRM1LMNA | |
| SCHEMBL8731834 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10TOP2A | |
| SCHEMBL7011663 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8735858 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8735880 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1TOP2ATOP2BTOP1 | |
| SCHEMBL9098398 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL3720416 | 0.78 | TOP2A (0.58) | KDM4EALDH1A1HPGDHSD17B10TOP2A | |
| SCHEMBL12427278 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |